Article
Association of Vascular Endothelial Growth Factor A (VEGFA) and its Receptor (VEGFR2) Gene Polymorphisms with Risk of Chronic Myeloid Leukemia and Influence on Clinical Outcome.
Molecular diagnosis & therapy - 1 Feb 2016
Lakkireddy Samyuktha, Aula Sangeetha, Kapley Atya, Swamy A V N, Digumarti Raghunadha Rao, Kutala Vijay Kumar, Jamil Kaiser
Abstract excerpt
INTRODUCTION: Vascular endothelial growth factor A (VEGFA) and its kinase insert domain receptor (VEGFR2/KDR) were reported to be upregulated in chronic myeloid leukemia (CML); however, the influence of polymorphisms in VEGFA and VEGFR2 in CML pathogenesis and therapeutic response, have not yet been elucidated. METHODS: We aimed to analyze these polymorphisms in 212 CML patients and 212 healthy controls by the...
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