Article

miR-148a-3p inhibits DNMT1-mediated methylation of VEGF and promotes proliferation and invasion in glioma cells via the PI3K/Akt/eNOS signaling pathway

2020-03-24

Abstract excerpt

<title>Abstract</title> <p>Background: Abnormal DNA methylation in the promoter region of vascular endothelial growth factor (VEGF) has been observed in multiple types of cancer. Increasing evidence shows that miR-148a-3p is involved in the regulation of methylation. However, it is unclear how miR-148a-3p regulates VEGF methylation. <h4>Methods:</h4> Methylation-specific polymerase chain reaction (MSP) and bisulf...

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Literature Corpus work: 9de11f88-612d-514e-8790-9ce55150ece6
DOI: 10.21203/rs.3.rs-18747/v1

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