Article
Interleukin-1ß and interleukin-1 receptor accessory protein gene polymorphisms are associated with persistent hepatitis B virus infection.
Hepato-gastroenterology - 1 Jan 2000
Kim Soon Sun, Cheong Jae Youn, Lee Dami, Lee Seung Ku, Kim Min-Ho, Kwack Kyubum, Yang Song-Ju, Lee Hyun-Young, Cho Sung Won
Abstract excerpt
BACKGROUND/AIMS: The reasons for persistent HBV infection are unknown, but they are probably related to host immune factors. IL-1ß plays significant roles in inflammation and immune defense via IL-1RAcP. We investigated whether genetic polymorphisms of IL-1ß and IL-1RAcP genes are associated with persistent HBV infection and the presence of HCC. METHODOLOGY: We enrolled a total of 292 patients with chronic HBV...
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