Article
Serum level of IP-10 increases predictive value of IL28B polymorphisms for spontaneous clearance of acute HCV infection.
Gastroenterology - 1 Jan 2012
Beinhardt Sandra, Aberle Judith H, Strasser Michael, Dulic-Lakovic Emina, Maieron Andreas, Kreil Anna, Rutter Karoline, Staettermayer Albert F, Datz Christian, Scherzer Thomas M, Strassl Robert, Bischof Martin, Stauber Rudolf, Bodlaj Gerd, Laferl Hermann, Holzmann Heidemarie, Steindl-Munda Petra, Ferenci Peter, Hofer Harald
Abstract excerpt
BACKGROUND & AIMS: Single nucleotide polymorphisms (SNPs) in IL28B and serum levels of interferon γ inducible protein 10 (IP-10) predict outcomes of antiviral therapy in patients with chronic hepatitis C. We associated IL28B SNPs rs12979860 and rs8099917, along with serum levels of IP-10, with outcomes of patients with acute hepatitis C (AHC). METHODS: We studied 120 patients with AHC (64 male; 37 ± 16 years old)...
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