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Article

COMT val158met polymorphism and neural pain processing.

PloS one - 1 Jan 2012

Schmahl Christian, Ludäscher Petra, Greffrath Wolfgang, Kraus Anja, Valerius Gabriele, Schulze Thomas G, Treutlein Jens, Rietschel Marcella, Smolka Michael N, Bohus Martin

Abstract excerpt

A functional polymorphism (val158met) of the gene coding for Catechol-O-methyltransferase (COM) has been demonstrated to be related to processing of emotional stimuli. Also, this polymorphism has been found to be associated with pain regulation in healthy subjects. Therefore, we investigated a po...

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Identifiers

PMID: 22247753
DOI: 10.1371/journal.pone.0023658
PMCID: PMC3256133

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22247753-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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