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Article

Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2015

Peciña Marta, Love Tiffany, Stohler Christian S, Goldman David, Zubieta Jon-Kar

Abstract excerpt

Mu-opioid receptors (MOPRs) are critically involved in the modulation of pain and analgesia, and represent a candidate mechanism for the development of biomarkers of pain conditions and their responses to treatment. To further understand the human implications of genetic variation within the opio...

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Source

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Identifiers

PMID: 25308352
DOI: 10.1038/npp.2014.272
PMCID: PMC4330509

Genes

OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25308352-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures.PMID 25308352Read ↗

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The OPRM1 A118G Polymorphism Revisited: Recent Developments and Implications for Personalized Treatment.Semantic proximity Read ↗

Effects of functional polymorphisms of opioid receptor mu 1 and catechol-O-methyltransferase on the neural processing of pain.Semantic proximity Read ↗

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Functional mu opioid receptor polymorphism (OPRM1 A(118) G) associated with heroin use outcomes in Caucasian males: A pilot study.Semantic proximity Read ↗

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