Article
Slug is upregulated during wound healing and regulates cellular phenotypes in corneal epithelial cells.
Investigative ophthalmology & visual science - 16 Feb 2012
Aomatsu Keiichi, Arao Tokuzo, Abe Kosuke, Kodama Aya, Sugioka Koji, Matsumoto Kazuko, Kudo Kanae, Kimura Hideharu, Fujita Yoshihiko, Hayashi Hidetoshi, Nagai Tomoyuki, Shimomura Yoshikazu, Nishio Kazuto
Abstract excerpt
PURPOSE: The involvement of the epithelial mesenchymal transition (EMT) in the process of corneal wound healing remains largely unclear. The purpose of the present study was to gain insight into Slug expression and corneal wound healing. METHODS: Slug expression during wound healing in the murine cornea was evaluated using fluorescence staining in vivo. Slug or Snail was stably introduced into human corneal...
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