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Article

dsRNA Induced IFNβ-MMP13 Axis Drives Corneal Wound Healing.

Investigative ophthalmology & visual science - 1 Feb 2022

Lan Xihong, Zhang Wang, Zhu Jin, Huang Huaxing, Mo Kunlun, Guo Huizhen, Zhu Liqiong, Liu Jiafeng, Li Mingsen, Wang Li, Liu Chunqiao, Ji Jianping, Ouyang Hong

Abstract excerpt

Purpose: Cornea, the outermost transparent layer of the eye, is the first line of defense against external threats. Following injury, the wound healing response is crucial to corneal repair and regeneration, yet its underlying mechanism is poorly understood. Our study was designed to investigate the role of dsRNA and its regulatory network in corneal wound healing. Methods: A corneal wound healing model was...

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Identifiers

PMID: 35129588
DOI: 10.1167/iovs.63.2.14
PMCID: PMC8822365

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