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Article

LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis

8 Dec 2013

Abstract excerpt

Corneal integrity and transparency are indispensable for good vision. Cornea homeostasis is entirely dependent upon corneal stem cells, which are required for complex wound-healing processes that restore corneal integrity following epithelial damage. Here, we found that leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is highly expressed in the human holoclone-type corneal epithelial stem cell...

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Share to Corneal surgery and disorders
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PMID: 24316976
DOI: 10.1172/jci71488

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