Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem Cells

9 Jan 2012

Abstract excerpt

TCF4, a key transcription factor of Wnt signaling system, has been recently found to be essential for maintaining stem cells. However, its signaling pathway is not well elucidated. This study was to explore the functional roles and signaling pathway of TCF4 in maintaining adult stem cell properties using human corneal epithelial stem cells as a model. With immunofluorescent staining and real-time polymerase chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal Surgery and Treatments
Share to Ocular Surface and Contact Lens
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22232078
DOI: 10.1002/stem.1032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem CellsPMID 22232078Read ↗

Wnt/β-catenin signaling regulates proliferation of human cornea epithelial stem/progenitor cells.Semantic proximity Read ↗

Wnt7a can up-regulates cell adhesion related protein fibronectin expression and promotes cell proliferation in corneal epithelial cellsSemantic proximity Read ↗

Single-Cell Transcriptomics Identifies a Unique Entity and Signature Markers of Transit-Amplifying Cells in Human Corneal LimbusSemantic proximity Read ↗

Frizzled 7 Maintains the Undifferentiated State of Human Limbal Stem/Progenitor CellsSemantic proximity Read ↗

Transcription factor profiling identifies Sox9 as regulator of proliferation and differentiation in corneal epithelial stem/progenitor cellsSemantic proximity Read ↗

Regulation and clinical implications of corneal epithelial stem cellsSemantic proximity Read ↗

Transcription factor TFAP2B up-regulates human corneal endothelial cell–specific genes during corneal development and maintenanceSemantic proximity Read ↗

PAX6 regulates human corneal epithelium cell identitySemantic proximity Read ↗

WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesisSemantic proximity Read ↗

Comparison of upstream regulators in human ex vivo cultured cornea limbal epithelial stem cells and differentiated corneal epithelial cellsSemantic proximity Read ↗

Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cellsSemantic proximity Read ↗

Control of Breast Cancer Growth and Initiation by the Stem Cell–Associated Transcription Factor TCF3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.