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Article

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2012

Funk Steven Daniel, Yurdagul Arif, Albert Patrick, Traylor James G, Jin Long, Chen Jin, Orr A Wayne

Abstract excerpt

OBJECTIVE: Endothelial cell activation results in altered cell-cell interactions with adjacent endothelial cells and with infiltrating leukocytes. Eph receptors and their ephrin ligands regulate cell-cell interactions during tissue remodeling, and multiple proinflammatory mediators induce endothelial EphA receptor and ephrinA ligand expression. Therefore, we sought to elucidate the role of EphA receptors and...

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Identifiers

PMID: 22247258
DOI: 10.1161/ATVBAHA.111.242792
PMCID: PMC3325141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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