Article
An in-house HIV genotyping assay for the detection of drug resistance mutations in Southeast Asian patients infected with HIV-1.
Journal of medical virology - 1 Mar 2012
Lee Chun Kiat, Lee Hong Kai, Loh Tze Ping, Sethi Sunil Kumar, Koay Evelyn Siew-Chuan, Tang Julian Wei-Tze
Abstract excerpt
Genotyping for HIV drug resistance is costly and beyond the means for many Southeast Asian patients, who are self-funded. This prompted the development of a more cost-effective, in-house assay for an ethnically diverse, Southeast Asian population at the National University Hospital in Singapore, using Sanger-based sequencing. Plasma samples from 20 treatment-failure patients with a broad spectrum of HIV drug...
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