Article
Comparative evaluation of the ViroSeq™ HIV-1 genotyping system and an in-house method for analysis of HIV-1 drug-resistance mutations in China.
Molecular diagnosis & therapy - 1 Feb 2011
Xu Sihong, Zhong Ping, Li Jingyun, Song Aijing, Li Hanping, Nie Jianhui, Li Xiuhua, Wang Youchun
Abstract excerpt
BACKGROUND AND OBJECTIVE: With the introduction of the ViroSeq™ HIV-1 Genotyping System (ViroSeq™ assay) into China, it is important to evaluate the impact of the diversity of HIV-1 genotypes found in China on the performance of the ViroSeq™ assay compared with an in-house method. MATERIALS AND METHODS: A total of 318 plasma samples, collected from 206 HIV-1-infected patients receiving antiretroviral therapy and...
Topics
- Anti-Retroviral Agents
- China
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- Humans
- Mutation
- Protease Inhibitors
- Reverse Transcriptase Inhibitors
- Sequence Analysis, RNA