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Article

A simple and sensitive 'in-house' method for determining genotypic drug resistance in HIV-1.

Journal of virological methods - 1 Jan 2003

Lindström Anna, Albert Jan

Abstract excerpt

Antiretroviral combination therapy is a major advance in the treatment of HIV infection, but development of antiretroviral resistance is still an important cause of treatment failure. Therefore, resistance testing was recommended recently for follow-up of HIV-1 infected individuals. The aim of this study was to develop a new genotypic resistance assay because simple and affordable assays with sufficient...

Topics

Amino Acid Sequence
DNA, Complementary
Drug Resistance, Viral
Genotype
HIV-1
Humans
Microbiological Techniques
Molecular Sequence Data
Polymerase Chain Reaction
RNA, Viral
Sensitivity and Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12445937
DOI: 10.1016/s0166-0934(02)00188-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12445937-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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