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Article

Predicting the adaptive evolution of Thermoanaerobacterium saccharolyticum.

Journal of biotechnology - 30 Apr 2012

Unrean Pornkamol, Srienc Friedrich

Abstract excerpt

A fully evolved metabolic network can be described as a weighted sum of elementary modes where the usage probabilities of modes are distributed according to the Boltzmann distribution law (Srienc and Unrean, 2010). An organism presumably achieves the fully evolved state through adaptive changes in the kinetics of rate-controlling enzymes. Metabolic control analysis identifies reactions catalyzed by such enzymes....

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PMID: 22245634
DOI: 10.1016/j.jbiotec.2011.12.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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