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Article

Recipient CTLA-4*CT60-AA genotype is a prognostic factor for acute graft-versus-host disease in hematopoietic stem cell transplantation for thalassemia.

Human immunology - 1 Mar 2012

Orrù Sandro, Orrù Nicola, Manolakos Emmanouil, Littera Roberto, Caocci Giovanni, Giorgiani Giovanna, Bertaina Alice, Pagliara Daria, Giardini Claudio, Nesci Sonia, Locatelli Franco, Carcassi Carlo, La Nasa Giorgio

Abstract excerpt

Polymorphisms of the cytotoxic T-lymphocyte antigen-4 gene (CTLA-4) have been associated with autoimmune diseases and it has recently been reported that donor genotypes correlate with the outcome of allogeneic hematopoietic stem cell transplantation in leukemia patients. With the aim of confirming this finding in thalassemia patients, we investigated the influence of genotype distribution of 3 CTLA-4 gene...

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Identifiers

PMID: 22245568
DOI: 10.1016/j.humimm.2011.12.014
PMCID: PMC3314940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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