Article
CTLA-4 +49A>G polymorphism of recipients of HLA-matched sibling allogeneic stem cell transplantation is associated with survival and relapse incidence.
Annals of hematology - 1 Jun 2010
Piccioli Patrizia, Balbi Giuseppe, Serra Martina, Morabito Anna, Lamparelli Teresa, Gobbi Marco, Laurent Stefania, Dozin Beatrice, Bruzzi Paolo, Ferraris Anna Maria, Bacigalupo Andrea, Notaro Rosario, Pistillo Maria Pia
Abstract excerpt
Conflicting observations have been reported about the role of CTLA-4 gene polymorphisms in the clinical outcome of allogeneic hematopoietic stem cell transplantation (HSCT). We have investigated three polymorphisms of the CTLA-4 gene (-318C>T, +49A>G, CT60G>A) in 133 donor/recipient pairs who und...
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