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Article

CTLA-4 polymorphism and clinical outcome post allogeneic hematopoietic stem cell transplantation.

Human immunology - 1 Dec 2013

Mossallam Ghada I, Samra Mohamed A

Abstract excerpt

CTLA-4 inhibitory molecule plays an important role in regulating T cell activation. It is considered a crucial element in keeping the immune balance and has been implicated in cancer, autoimmunity and transplantation immunology. Inconsistent observations are reported regarding its association with hematopoietic stem cell transplantation (HSCT). Genotyping of CTLA-4 was performed in recipients and their...

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Identifiers

PMID: 23973330
DOI: 10.1016/j.humimm.2013.08.002

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