Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alzheimer's disease risk factor complement receptor 1 is associated with depression.

Neuroscience letters - 21 Feb 2012

Hamilton Gillian, Evans Kathryn L, Macintyre Donald J, Deary Ian J, Dominiczak Anna, Smith Blair H, Morris Andrew D, Porteous David J, Thomson Pippa A

Abstract excerpt

Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease
Share to Depression
Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study
Share to Haplotypes
Share to Polymorphism, Single Nucleotide
Share to Receptors, Complement
Share to Scotland

Source

Identifiers

PMID: 22244847
DOI: 10.1016/j.neulet.2011.12.059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alzheimer's disease risk factor complement receptor 1 is associated with depression.PMID 22244847Read ↗

CR1 in Alzheimer's disease.Semantic proximity Read ↗

Complement receptor 1 (CR1) and Alzheimer's disease.Semantic proximity Read ↗

Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites.Semantic proximity Read ↗

An Updated Analysis with 85,939 Samples Confirms the Association Between CR1 rs6656401 Polymorphism and Alzheimer's Disease.Semantic proximity Read ↗

Complement receptor 1 genetic polymorphism contributes to sporadic Alzheimer's disease susceptibility in Caucasians: a meta-analysis.Semantic proximity Read ↗

Explore the role of CR1 genetic variants in late-onset Alzheimer's disease susceptibility.Semantic proximity Read ↗

Genetic association of CR1 with Alzheimer's disease: a tentative disease mechanism.Semantic proximity Read ↗

Impacts of CR1 genetic variants on cerebrospinal fluid and neuroimaging biomarkers in alzheimer's disease.Semantic proximity Read ↗

Genetic Insights into the Impact of Complement in Alzheimer's Disease.Semantic proximity Read ↗

Association of the CR1 polymorphism with late-onset Alzheimer's disease in Chinese Han populations: a meta-analysis.Semantic proximity Read ↗

Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function.Semantic proximity Read ↗

Complement receptor 1 polymorphisms and risk of late-onset Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.