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Article

D2 receptor density and prepulse inhibition in humans: negative findings from a molecular genetic approach.

Behavioural brain research - 5 Mar 2008

Montag Christian, Hartmann Peter, Merz Michael, Burk Christian, Reuter Martin

Abstract excerpt

There is plenty of evidence from schizophrenia research and psychopharmacological experiments showing the influence of the dopaminergic neurotransmission on the prepulse inhibition (PPI). A lot of insights into the underlying neural mechanisms of the PPI have been gained from animal models, which are in need to be validated in humans. Due to new technological advances, findings from psychopharmacological...

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Topics

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Share to Acoustic Stimulation
Share to Conditioning, Classical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inhibition, Psychological

Share to Menstrual Cycle

Share to Neural Inhibition

Share to Reaction Time

Share to Receptors, Dopamine D2

Share to Reflex, Startle

Source

Identifiers

PMID: 18037170
DOI: 10.1016/j.bbr.2007.10.006

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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D2 receptor density and prepulse inhibition in humans: negative findings from a molecular genetic approach.PMID 18037170Read ↗

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Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism.Semantic proximity Read ↗

Genetic variation of serotonin receptor function affects prepulse inhibition of the startle.Semantic proximity Read ↗

The dopamine D(3) receptor Ser9Gly polymorphism modulates prepulse inhibition of the acoustic startle reflex.Semantic proximity Read ↗

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