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Article

Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila.

Science (New York, N.Y.) - 29 Sept 2000

Pham A D, Sauer F

Abstract excerpt

Ubiquitination of histones has been linked to the complex processes that regulate the activation of eukaryotic transcription. However, the cellular factors that interpose this histone modification during the processes of transcriptional activation are not well characterized. A biochemical approach identified the Drosophila coactivator TAFII250, the central subunit within the general transcription factor TFIID, as...

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Identifiers

PMID: 11009423
DOI: 10.1126/science.289.5488.2357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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