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Article

The complexity of PRC2 catalysts CLF and SWN in plants.

Biochemical Society transactions - 18 Dec 2020

Shu Jie, Chen Chen, Li Chenlong, Cui Yuhai

Abstract excerpt

Polycomb repressive complex 2 (PRC2) is an evolutionally conserved multisubunit complex essential for the development of eukaryotes. In Arabidopsis thaliana (Arabidopsis), CURLY LEAF (CLF) and SWINGER (SWN) are PRC2 catalytic subunits that repress gene expression through trimethylating histone H3 at lysine 27 (H3K27me3). CLF and SWN function to safeguard the appropriate expression of key developmental regulators...

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PMID: 33170267
DOI: 10.1042/BST20200660

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