Article
Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease.
The Journal of infectious diseases - 15 Feb 2012
Taylor Brandie D, Darville Toni, Ferrell Robert E, Kammerer Candace M, Ness Roberta B, Haggerty Catherine L
Abstract excerpt
BACKGROUND: Toll-like receptors (TLRs) are involved in the innate immune response. We examined whether TLR variants are associated with Chlamydia trachomatis infection among women with pelvic inflammatory disease (PID). METHODS: We tested whether 18 tagging single nucleotide polymorphisms (tagSNPs) assayed in 4 TLR genes (TLR1, TLR2, TLR4, TLR6) and 2 adaptor molecules (TIRAP, MyD88) were associated with C....
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