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Article

TLR2, TLR4 and TLR9 genotypes and haplotypes in the susceptibility to and clinical course of Chlamydia trachomatis infections in Dutch women.

Pathogens and disease - 1 Feb 2016

Verweij Stephan P, Karimi Ouafae, Pleijster Jolein, Lyons Joseph M, de Vries Henry J C, Land Jolande A, Morré Servaas A, Ouburg Sander

Abstract excerpt

Chlamydia trachomatis infections demonstrate remarkable differences in clinical course that are approximately 40% based on host genetic variation. Here, we study the single nucleotide polymorphisms (SNPs) and their haplotypes in TLR2, TLR4 and TLR9 (TLR2 +2477G>A; TLR2 -16934T>A; TLR4+896A>G; TLR9 -1237T>C and TLR9 +2848G>A) in relation to the susceptibility to, and severity of C. trachomatis infections. We...

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Identifiers

PMID: 26568059
DOI: 10.1093/femspd/ftv107
PMCID: PMC4882084

Genes

TLR2
TLR9
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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