Article
Do host genetic traits in the bacterial sensing system play a role in the development of Chlamydia trachomatis-associated tubal pathology in subfertile women?
BMC infectious diseases - 21 Jul 2006
den Hartog Janneke E, Ouburg Sander, Land Jolande A, Lyons Joseph M, Ito James I, Peña A Salvador, Morré Servaas A
Abstract excerpt
BACKGROUND: In women, Chlamydia (C.) trachomatis upper genital tract infection can cause distal tubal damage and occlusion, increasing the risk of tubal factor subfertility and ectopic pregnancy. Variations, like single nucleotide polymorphisms (SNPs), in immunologically important host genes are assumed to play a role in the course and outcome of a C. trachomatis infection. We studied whether genetic traits...
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