Article
Genetic association of Toll-like receptor 4 with cervical cytokine concentrations during pregnancy.
Genes and immunity - 1 Oct 2009
Ryckman K K, Williams S M, Krohn M A, Simhan H N
Abstract excerpt
Toll-like receptors (TLRs) are critical components of innate immunity, recognizing bacterial microorganisms and initiating local inflammatory responses. In this study, we assessed the impact of genetic variation in TLR genes on cervical concentrations of pro- and anti-inflammatory cytokines, and determined whether this relationship is influenced by bacterial vaginosis (BV). A total of 4 single nucleotide...
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