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Article

Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.

PloS one - 22 Jun 2009

Hawn Thomas R, Scholes Delia, Li Shuying S, Wang Hongwei, Yang Yin, Roberts Pacita L, Stapleton Ann E, Janer Marta, Aderem Alan, Stamm Walter E, Zhao Lue Ping, Hooton Thomas M

Abstract excerpt

BACKGROUND: Although behavioral risk factors are strongly associated with urinary tract infection (UTI) risk, the role of genetics in acquiring this disease is poorly understood. METHODOLOGY/PRINCIPAL FINDINGS: To test the hypothesis that polymorphisms in Toll-like receptor (TLR) pathway genes are associated with susceptibility to UTIs, we conducted a population-based case-control study of women ages 18-49 years....

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Identifiers

PMID: 19543401
DOI: 10.1371/journal.pone.0005990
PMCID: PMC2696082

Genes

TLR1
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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