Article
Association of CCR5, TLR2, TLR4 and MBL genetic variations with genital tract infections and tubal factor infertility.
Journal of reproductive immunology - 1 Dec 2010
Laisk Triin, Peters Maire, Saare Merli, Haller-Kikkatalo Kadri, Karro Helle, Salumets Andres
Abstract excerpt
Upper genital tract infections can inflict inadequate immune response and cause Fallopian tube damage and concomitant female infertility. However, the exact role of host genetic variation in the development of tubal factor infertility remains unclear. We selected nine genetic variations in four genes involved in immune response modulation (CCR5, TLR2, TLR4 and MBL2) and assessed their association with tubal...
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