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Article

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome.

Nucleic acids research - 1 May 2012

Rorbach Joanna, Gammage Payam A, Minczuk Michal

Abstract excerpt

Defects of the translation apparatus in human mitochondria are known to cause disease, yet details of how protein synthesis is regulated in this organelle remain to be unveiled. Here, we characterize a novel human protein, C7orf30 that contributes critically to mitochondrial translation and specifically associates with the large subunit of the mitochondrial ribosome (mt-LSU). Inactivation of C7orf30 in human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22238376
DOI: 10.1093/nar/gkr1282
PMCID: PMC3351152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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