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Article

Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesis.

Transgenic research - 1 Oct 2012

Wu Xiaoli, Sandhu Sumit, Nabi Zinnatun, Ding Hao

Abstract excerpt

Regulator of telomere length 1 (RTEL1) is a DNA helicase protein that has been demonstrated to be required for the maintenance of telomere length and genomic stability. It has also been found to be essential for DNA homologous recombination during DNA repairing. Human RTEL1 genomic locus (20q13.3...

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Source

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Identifiers

PMID: 22238064
DOI: 10.1007/s11248-011-9586-7
PMCID: PMC3432790

Genes

RTEL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22238064-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesis.PMID 22238064Read ↗

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