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Article

Negative/low HER2 expression alone or combined with E-cadherin positivity is predictive of better prognosis in patients with breast carcinoma.

Histology and histopathology - 1 Mar 2012

Karray-Chouayekh Sondes, Trifa Fatma, Khabir Abdelmajid, Sellami-Boudawara Tahia, Frikha Mounir, Gargouri Ali, Mokdad-Gargouri Raja

Abstract excerpt

The loss of E-cadherin expression leads to absence of tissue integrity, an essential step in tumor progression. Methylation of CpG islands in the promoter region of the CDH1 gene coding E-cadherin might be an alternative for gene silencing. In the present study, we investigate the expression of E-cadherin and hormone receptors in invasive ductal breast carcinoma (IDCs). Protein expression was analysed...

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Identifiers

PMID: 22237715
DOI: 10.14670/HH-27.377

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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