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Article

c-KIT receptor expression is strictly associated with the biological behaviour of thyroid nodules.

Journal of translational medicine - 10 Jan 2012

Tomei Sara, Mazzanti Chiara, Marchetti Ivo, Rossi Leonardo, Zavaglia Katia, Lessi Francesca, Apollo Alessandro, Aretini Paolo, Di Coscio Giancarlo, Bevilacqua Generoso

Abstract excerpt

BACKGROUND: A large amount of information has been collected on the molecular tumorigenesis of thyroid cancer. A low expression of c-KIT gene has been reported during the transformation of normal thyroid epithelium to papillary carcinoma suggesting a possible role of the gene in the differentiation of thyroid tissue rather than in the proliferation. The initial presentation of thyroid carcinoma is through a...

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Source

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Identifiers

PMID: 22233760
DOI: 10.1186/1479-5876-10-7
PMCID: PMC3267663

Genes

KIT
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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