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Article

[Molecular Pathogenesis of Thyroid Nodules: Relevance for Clinical Care].

Laryngo- rhino- otologie - 1 Sept 2017

Führer D, Musholt T, Schmid K W

Abstract excerpt

Thyroid nodules represent heterogeneous tumors with distinct molecular signatures. While benign thyroid nodules correspond to poly- or monoclonal tumors, thyroid carcinomas are monoclonal and thus "real" neoplasms. These are caused by somatic mutations that lead to the constitutive activation of specific signaling cascades and determine the corresponding histology and also partly the functional phenotype of the...

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Source

Identifiers

PMID: 28881369
DOI: 10.1055/s-0043-109180

Genes

BRAF
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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