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Article

Relevance of BRAF(V600E) mutation testing versus RAS point mutations and RET/PTC rearrangements evaluation in the diagnosis of thyroid cancer.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2015

Rossi Martina, Buratto Mattia, Tagliati Federico, Rossi Roberta, Lupo Sabrina, Trasforini Giorgio, Lanza Giovanni, Franceschetti Paola, Bruni Stefania, Degli Uberti Ettore, Zatelli Maria Chiara

Abstract excerpt

BACKGROUND: A molecular profile including BRAF and RAS mutations as well as RET/PTC rearrangement evaluation has been proposed to provide an accurate presurgical assessment of thyroid nodules and to reduce the number of unnecessary diagnostic surgeries, sparing patients' health and saving healthcare resources. However, the application of such molecular analyses may provide different results among different...

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-ret

Share to ras Proteins

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Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25333496
DOI: 10.1089/thy.2014.0338
PMCID: PMC4322031

Genes

RET
BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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