Article
Exonuclease 1 (EXO1) gene variation and melanoma risk.
DNA repair - 1 Mar 2012
Song Fengju, Qureshi Abrar A, Zhang Jiangwen, Zhan Jiangwen, Amos Christopher I, Lee Jeffrey E, Wei Qingyi, Han Jiali
Abstract excerpt
OBJECTIVE: DNA repair pathway genes play an important role in maintaining genomic integrity and protecting against cancer development. This study aimed to identify novel SNPs in the DNA repair-related genes associated with melanoma risk from a genome-wide association study (GWAS). METHODS: A total of 8422 SNPs from the 165 DNA repair-related genes were extracted from a GWAS of melanoma risk, including 494 cases...
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