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Article

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.

Pharmacogenetics and genomics - 1 Mar 2012

Aslibekyan Stella, Kabagambe Edmond K, Irvin Marguerite R, Straka Robert J, Borecki Ingrid B, Tiwari Hemant K, Tsai Michael Y, Hopkins Paul N, Shen Jian, Lai Chao-Qiang, Ordovas Jose M, Arnett Donna K

Abstract excerpt

OBJECTIVE: Despite the evidence in support of the anti-inflammatory and triglyceride-lowering effects of fenofibrate, little is known about genetic determinants of the observed heterogeneity in treatment response. This study provides the first genome-wide examination of fenofibrate effects on systemic inflammation. METHODS: Biomarkers of inflammation were measured in participants of the Genetics of Lipid Lowering...

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Identifiers

PMID: 22228203
DOI: 10.1097/FPC.0b013e32834fdd41
PMCID: PMC3275691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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