Article
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Oct 2013
Aslibekyan S, An P, Frazier-Wood A C, Kabagambe E K, Irvin M R, Straka R J, Tiwari H K, Tsai M Y, Hopkins P N, Borecki I B, Ordovas J M, Arnett D K
Abstract excerpt
BACKGROUND AND AIMS: Adiponectin is an adipose-secreted protein that has been linked to changes in insulin sensitivity, high-density lipoprotein cholesterol levels, and inflammatory patterns. Although fenofibrate therapy can raise adiponectin levels, treatment response is heterogeneous and heritable, suggesting a role for genetic mediators. This is the first genome-wide association study of fenofibrate effects on...
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