Article
Allelic variations of human TCR V gene products.
Immunology today - 1 Oct 1990
Posnett D N
Abstract excerpt
A central problem confronting the immune system is how to discriminate among vast numbers of antigens. Novel genetic ploys that aid the discriminative process, including complex gene rearrangements (in antibody and T-cell receptor (TCR) genes) and extensive allelic polymorphism (in major histocompatibility complex (MHC) genes), have been described. Recent evidence has suggested a further level of diversity; TCR V...
Topics
- Alleles
- Humans
- Introns
- Major Histocompatibility Complex
- Polymorphism, Genetic
- Receptors, Antigen, T-Cell
- Recombination, Genetic
