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Article

Causes of alternative pathway dysregulation in dense deposit disease.

Clinical journal of the American Society of Nephrology : CJASN - 1 Feb 2012

Zhang Yuzhou, Meyer Nicole C, Wang Kai, Nishimura Carla, Frees Kathy, Jones Michael, Katz Louis M, Sethi Sanjeev, Smith Richard J H

Abstract excerpt

BACKGROUND AND OBJECTIVES: This study was designed to investigate the causes of alternative pathway dysregulation in a cohort of patients with dense deposit disease (DDD). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Thirty-two patients with biopsy-proven DDD underwent screening for C3 nephritic factors (C3Nefs), factor H autoantibodies (FHAAs), factor B autoantibodies (FBAAs), and genetic variants in CFH....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulonephritis, Membranoproliferative

Source

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Identifiers

PMID: 22223606
DOI: 10.2215/CJN.07900811
PMCID: PMC3280037

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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