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Alternative pathway diagnostics

28 Oct 2022

Abstract excerpt

Uncontrolled alternative pathway activation is the primary driver of several diseases, and it contributes to the pathogenesis of many others. Consequently, diagnostic tests to monitor this arm of the complement system are increasingly important. Defects in alternative pathway regulation are strong risk factors for disease, and drugs that specifically block the alternative pathway are entering clinical use. A...

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PMID: 36305168
DOI: 10.1111/imr.13156

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