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Article

Spectra of BRCA1 and BRCA2 mutations in Korean patients with breast cancer: the importance of whole-gene sequencing.

Journal of human genetics - 1 Mar 2012

Jang Ja-Hyun, Lee Jeong Eon, Kwon Min-Jung, Ki Chang-Seok, Kim Jong-Won, Nam Seok Jin, Yang Jung-Hyun

Abstract excerpt

The frequencies and spectra of germline mutations in the BRCA1 and BRCA2 genes vary among populations. In the present study, the mutation spectra of the BRCA1/BRCA2 genes in Korean breast cancer patients were investigated using whole-gene sequencing method. A total of 134 unrelated Korean breast cancer patients who were identified as being at high risk of carrying BRCA1/BRCA2 mutations were included. PCR...

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Source

Identifiers

PMID: 22217648
DOI: 10.1038/jhg.2011.139

Genes

BRCA2
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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