Article
Prevalence of BRCA1 and BRCA2 mutations in Korean breast cancer patients.
Journal of Korean medical science - 1 Apr 2004
Ahn Sei Hyun, Hwang Ui Kang, Kwak Beom Seok, Yoon Ho Sung, Ku Bo Kyung, Kang Hee Jun, Kim Ji Su, Ko Byung Kyun, Ko Chang Dae, Yoon Kyung Sik, Cho Dae-Yeon, Kim Jun Suk, Son Byung Ho
Abstract excerpt
The incidence of breast cancer in Korea has been increasing in recent years, such that it is now the most common female cancer. Breast cancer in Korea is characterized by an earlier age of onset than in Western countries, suggesting that it would be related with genetic background. We assayed germline mutations in the BRCA genes to evaluate their genetic pathology in Korean breast cancer patients. The study...
Topics
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Germ-Line Mutation
- Humans
- Korea
- Point Mutation
- Prevalence
- Risk Factors
