Article
Prevalence of BRCA1 and BRCA2 mutations in non-familial breast cancer patients with high risks in Korea: the Korean Hereditary Breast Cancer (KOHBRA) Study.
Breast cancer research and treatment - 1 Jun 2012
Son Byung Ho, Ahn Sei Hyun, Kim Sung-Won, Kang Eunyoung, Park Sue K, Lee Min Hyuk, Noh Woo-Chul, Kim Lee Su, Jung Yongsik, Kim Ku Sang, Noh Dong-Young, Moon Byung-In, Suh Young Jin, Lee Jeong Eon, Choi Doo Ho, Kim Sung Yong, Jung Sung Hoo, Yom Cha Kyong, Lee Hyde, Yang Jung-Hyun
Abstract excerpt
Prevalence and phenotype of BRCA mutation can vary by race. The purpose of this study is to evaluate the prevalence of BRCA1/2 mutations in non-familial breast cancer patients with high risks in Korea. A subset of 758 patients was selected for this study from the KOHBRA nationwide multicenter prospective cohort study. Mutations in BRCA1/2 genes were tested using fluorescent-conformation sensitive gel...
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