Article
Future treatment of chronic hepatitis C with direct acting antivirals: is resistance important?
Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2012
Halfon Philippe, Sarrazin Christoph
Abstract excerpt
Recent advances in molecular biology have led to the development of novel small molecules that target specific viral proteins of the hepatitis C virus (HCV) life cycle. These drugs, collectively termed directly acting antivirals (DAA), include a range of non-structural (NS) 3/NS4A protease, NS5B polymerase and NS5A inhibitors at various stages of clinical development. Some others drugs called 'non DAA'or indirect...
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