Article
Determinants of public T cell responses.
Cell research - 1 Jan 2012
Li Hanjie, Ye Congting, Ji Guoli, Han Jiahuai
Abstract excerpt
Historically, sharing T cell receptors (TCRs) between individuals has been speculated to be impossible, considering the dramatic discrepancy between the potential enormity of the TCR repertoire and the limited number of T cells generated in each individual. However, public T cell response, in which multiple individuals share identical TCRs in responding to a same antigenic epitope, has been extensively observed...
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