Article

Identification, crystallization and epitope determination of public TCR shared and expanded in COVID-19 patients

2021-03-23

Abstract excerpt

<h4>Summary</h4> T cells play pivotal roles in protective immunity against SARS-CoV-2 infection. Follicular helper T (Tfh) cells mediate the production of antigen-specific antibodies; however, T cell receptor (TCR) clonotypes used by SARS-CoV-2-specific Tfh cells have not been well characterized. Here, we first identified and crystallized public TCR of Tfh clonotypes that are shared and expanded in unhospitalized...

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Literature Corpus work: b208ffc6-a7a9-5f6f-8b99-a555c93af29d
DOI: 10.1101/2021.03.23.436573

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