Article
Common variation in genes related to immune response and risk of childhood leukemia.
Human immunology - 1 Mar 2012
Han Sohee, Koo Hong Hoe, Lan Qing, Lee Kyoung-Mu, Park Ae Kyung, Park Sue K, Sung Hyuna, Ahn Hyo Seop, Shin Hee Young, Kang Hyoung Jin, Seo Jong Jin, Ahn Yoon-Ok, Kim Ho, Rothman Nathaniel, Kang Daehee
Abstract excerpt
An abnormal immune response to common infection(s) may be a plausible etiological mechanism in childhood leukemia. We investigated whether 931 tagging single nucleotide polymorphisms (SNPs) selected in gene regions related to immune response are associated with childhood leukemia susceptibility in a hospital-based case-control study (63 cases and 148 controls) conducted among Korean children. The AT or TT...
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