Article
Effect of a traditional Chinese medicine Liu Wei Di Huang Wan on the activities of CYP2C19, CYP2D6 and CYP3A4 in healthy volunteers.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Jun 2012
Chen Y, Ouyang D-S, Kang Z, Yang G-P, Tan Z-R, Zhou G, Yan J
Abstract excerpt
Liu Wei Di Huang Wan (LDW), a well-known traditional Chinese medicine, is widely used for the treatment of various diseases in China. This study was designed to investigate the potential herb-drug interactions of LDW in healthy volunteers and attempted to ascertain whether the interaction might be affected by genotypes. We assessed the effect of LDW on the activities of CYP2C19, CYP2D6 and CYP3A4 in 12...
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