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Article

Association of HLA-DRB1 Alleles with Rheumatic Fever and Rheumatic Heart Disease: A Meta-analysis.

Immunological investigations - 1 Feb 2022

Poomarimuthu Maheshkumar, Ramasamy Thirunavukkarasu, Govindan Ramajayam, Andiappan Rathinavel, Nagarajan Gunavathy, Kadiam Sony, Mariakuttikan Jayalakshmi

Abstract excerpt

BACKGROUND: Rheumatic fever (RF) and its sequel rheumatic heart disease (RHD) is an autoimmune disease caused by an abnormal host immune response to group A streptococcus (GAS) infection. The HLA class II molecules are entailed in immune-mediated infectious, inflammatory, and autoimmune diseases including RHD. However, HLA class II genes are reported to be associated with RF/RHD across different populations with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32967480
DOI: 10.1080/08820139.2020.1822864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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