Article
The omnipotent suppressor SUP45 affects nucleic acid metabolism and mitochondrial structure.
Yeast (Chichester, England) - 1 Jan 2000
Pocklington M J, Johnston L, Jenkins J R, Orr E
Abstract excerpt
Yeast (Saccharomyces cerevisiae) strains sensitive to a variety of drugs were used to select for novobiocin-resistant mutants that were simultaneously temperature-sensitive. The mutants remained as sensitive as the parent strains to a wide range of drugs other than novobiocin, and did not exhibit any suppression of suppressible auxotrophic markers. At the non-permissive temperature, the mutant cells arrested...
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